Personalized Dosing Instructions

ALWAYS follow your physician's prescribed treatment plan. Your Compounded Semaglutide (GLP-1) medication/Compounded Tirzepatide (GLP-1/GIP) medication is a once-a-week injection. Dosage increases are typically prescribed monthly, depending on your weight loss goals and how your body responds to the treatment.

Dosing Guide for Compounded Semaglutide (GLP-1) Injections 3mg/mL

(GLISS)

*2.22 mg is the maximum dose/maintenance dose for Compounded Semaglutide (GLP-1) Injections 3mg/mL **Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider.

WEEKLY DOSING	SIG / INJECTION INSTRUCTIONS
0.22 mg	Inject 7 units (0.22 mg) SQ weekly for weeks 1-4, Inject 15 units (0.44 mg) SQ weekly for weeks 5-8 Inject 30 units (0.89 mg) SQ weekly for weeks 9-12
0.44 mg	Inject 15 units (0.44 mg) SQ weekly for weeks 1-4 Inject 30 units (0.89 mg) SQ weekly for weeks 5-8 Inject 50 units (1.50 mg) SQ weekly for weeks 9-12
0.89 mg	Inject 30 units (0.89 mg) SQ weekly for weeks 1-4 Inject 50 units (1.50 mg) SQ weekly for weeks 5-8 Inject 67 units (2.00 mg) SQ weekly for weeks 9-12
1.5 mg	Inject 50 units (1.50 mg) SQ weekly for weeks 1-4 Inject 67 units (2.00 mg) SQ weekly for weeks 5-8 Inject 74 units (2.22 mg) SQ weekly for weeks 9-12
2 mg	Inject 67 units (2.00 mg) SQ weekly for weeks 1-4 Inject 74 units (2.22 mg) SQ weekly for weeks 5-8 Inject 74 units (2.22 mg) SQ weekly for weeks 9-12
2.22 mg	Inject 74 units (2.22 mg) SQ weekly for weeks 1-4 Inject 74 units (2.22 mg) SQ weekly for weeks 5-8 Inject 74 units (2.22 mg) SQ weekly for weeks 9-12

Dosing Guide for Compounded Tirzepatide (GLP-1/GIP) Injections 18mg/mL

(GLISS)

*15 mg is the maximum dose/maintenance dose for Compounded Tirzepatide (GLP-1/GIP) Injections 18mg/mL **Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider.

WEEKLY DOSING	SIG / INJECTION INSTRUCTIONS
2.22 mg	Inject 12 units (2.22 mg) SQ weekly for weeks 1-4 Inject 25 units (4.45 mg) SQ weekly for weeks 5-8 Inject 37 units (6.67 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
4.45 mg	Inject 25 units (4.45 mg) SQ weekly for weeks 1-4 Inject 37 units (6.67 mg) SQ weekly for weeks 5-8 Inject 49 units (8.9 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
6.67 mg	Inject 37 units (6.67 mg) SQ weekly for weeks 1-4 Inject 49 units (8.9 mg) SQ weekly for weeks 5-8 Inject 62 units (11.12 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
8.9 mg	Inject 49 units (8.90 mg) SQ weekly for weeks 1-4 Inject 62 units (11.12 mg) SQ weekly for weeks 5-8 Inject 74 units (13.35 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
11.12 mg	Inject 62 units (11.12 mg) SQ weekly for weeks 1-4 Inject 74 units (13.35 mg) SQ weekly for weeks 5-8 Inject 83 units (15 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
13.35 mg	Inject 74 units (13.35 mg) SQ weekly for weeks 1-4 Inject 83 units (15 mg) SQ weekly for weeks 5-8 Inject 83 units (15 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
15 mg	Inject 83 units (15 mg) SQ weekly for weeks 1-4 Inject 83 units (15 mg) SQ weekly for weeks 5-8 Inject 83 units (15 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider

Dosing Guide for Compounded Semaglutide (GLP-1) Injections 3mg/mL

(LOCUMTELE)

*2.22 mg is the maximum dose/maintenance dose for Compounded Semaglutide (GLP-1) Injections 3mg/mL **Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider.

WEEKLY DOSING	SIG / INJECTION INSTRUCTIONS
0.22 mg	Inject 7 units (0.22 mg) SQ weekly for weeks 1-4 Inject 15 units (0.44 mg) SQ weekly for weeks 5-8 Inject 15 units (0.44 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
0.44 mg	Inject 15 units (0.44 mg) SQ weekly for weeks 1-4 Inject 30 units (0.89 mg) SQ weekly for weeks 5-8 Inject 30 units (0.89 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
0.89 mg	Inject 30 units (0.89 mg) SQ weekly for weeks 1-4 Inject 50 units (1.50 mg) SQ weekly for weeks 5-8 Inject 50 units (1.50 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
1.5 mg	Inject 50 units (1.50 mg) SQ weekly for weeks 1-4 Inject 67 units (2.00 mg) SQ weekly for weeks 5-8 Inject 67 units (2.00 mg) SQ weekly for weeks 5-8 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
2 mg	Inject 67 units (2.00 mg) SQ weekly for weeks 1-4 Inject 74 units (2.22 mg) SQ weekly for weeks 5-8 Inject 74 units (2.22 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
2.22 mg	Inject 74 units (2.22 mg) SQ weekly for weeks 1-4 Inject 74 units (2.22 mg) SQ weekly for weeks 5-8 Inject 74 units (2.22 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider

Dosing Guide for Compounded Tirzepatide (GLP-1/GIP) Injections 18mg/mL

(LOCUMTELE)

*15 mg is the maximum dose/maintenance dose for Compounded Tirzepatide (GLP-1/GIP) Injections 18mg/mL **Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider.

WEEKLY DOSING	SIG / INJECTION INSTRUCTIONS
2.22 mg	Inject 12 units (2.22 mg) SQ weekly for weeks 1-4 Inject 25 units (4.45 mg) SQ weekly for weeks 5-8 Inject 25 units (4.45 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
4.45 mg	Inject 25 units (4.45 mg) SQ weekly for weeks 1-4 Inject 37 units (6.67 mg) SQ weekly for weeks 5-8 Inject 37 units (6.67 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
6.67 mg	Inject 37 units (6.67 mg) SQ weekly for weeks 1-4 Inject 49 units (8.9 mg) SQ weekly for weeks 5-8 Inject 49 units (8.9 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
8.9 mg	Inject 49 units (8.90 mg) SQ weekly for weeks 1-4 Inject 62 units (11.12 mg) SQ weekly for weeks 5-8 Inject 62 units (11.12 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
11.12 mg	Inject 62 units (11.12 mg) SQ weekly for weeks 1-4 Inject 74 units (13.35 mg) SQ weekly for weeks 5-8 Inject 74 units (13.35 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
13.35 mg	Inject 74 units (13.35 mg) SQ weekly for weeks 1-4 Inject 74 units (13.35 mg) SQ weekly for weeks 5-8 Inject 74 units (13.35 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider
15 mg	Inject 83 units (15 mg) SQ weekly for weeks 1-4 Inject 83 units (15 mg) SQ weekly for weeks 5-8 Inject 83 units (15 mg) SQ weekly for weeks 9-12 Increase dose beyond labeled instructions ONLY AS OR IF DIRECTED by provider

Evaluate side effects

Mild nausea, headaches, fatigue, constipation, and diarrhea are common when starting a new dosage and typically go away after a short period.

HOW WOULD YOU DESCRIBE YOUR SIDE EFFECTS?	NEXT STEP:
None or manageable • Side effects are mild to none • They don't disrupt your daily life	Continue to Step 2.
Unmanageable • Side effects interfere with your daily life	Discontinue treatment and get in touch with your doctor ASAP.